Artesunate
Physical properties
white crystal, melting point 1290°C-1400°C, odorless, bitter taste. Readily soluble in chloroform, soluble in acetone, slightly soluble in methanol or ethanol, and almost insoluble in water.
Plant source: Artemisia annua l. leaf
Action and use
It has a strong killing effect on plasmodium asexuality and can quickly control the onset of malaria. The mean transnegative time of vivax malaria and malignant protozoa was faster than that of chloroquine, and no toxic side effects were found in clinical treatment.
Dosage
Malaria can be treated by three days of injection therapy, the total amount of 0.9~1.2g, 0.3g intramuscular injection once a day, the first dose of severe patients doubled